Revised time estimation of the ancestral human chromosome 2 fusion
Abstract Background The reduction of the chromosome number from 48 in the Great Apes to 46 in modern humans is thought to result from the end-to-end fusion of two ancestral non-human primate chromosomes forming the human chromosome 2 (HSA2).Genomic signatures of this event are the presence of inverted telomeric repeats at the HSA2 fusion site and a